High-dose methotrexate is the backbone of various regimens for treating lymphoid malignancies.Mucositis is a well-known, dose-related side effect of methotrexate.Prophylactic measures such Microwave Thermistor as folinic acid rescue are useful but do not prevent mucositis in all the cases.Once severe mucositis (WHO Grade IV) sets in, mortality is Lipstick very high.
The index case highlights the natural course of methotrexate-induced mucositis and the need for swift and preemptive intervention.